KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
16.67
Human Site:
S695
Identified Species:
28.21
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S695
I
S
V
G
E
E
E
S
F
N
L
K
Q
K
V
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S695
I
S
M
G
E
E
E
S
F
N
L
K
Q
K
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
C695
I
S
M
G
E
K
E
C
F
S
L
K
Q
K
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
S695
V
C
A
G
E
K
E
S
Y
S
L
K
Q
K
V
Rat
Rattus norvegicus
NP_001101888
2143
241191
S695
V
C
A
G
E
K
E
S
Y
T
V
K
Q
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S695
I
L
V
A
E
M
E
S
D
S
V
K
Q
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
G691
C
D
I
L
S
R
Q
G
S
S
V
R
D
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
G691
L
Q
S
V
E
D
H
G
G
E
L
Y
I
Q
K
Honey Bee
Apis mellifera
XP_393800
2028
231830
M657
A
H
G
D
A
A
S
M
F
F
N
L
I
L
L
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
S341
W
K
I
L
K
E
L
S
E
R
T
D
T
T
K
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
Q326
L
P
G
K
V
M
F
Q
I
C
A
L
P
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
D656
I
S
M
D
I
I
N
D
L
G
E
A
L
S
L
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
K460
D
P
V
E
T
T
K
K
D
T
A
S
F
Q
T
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
K479
A
E
D
N
N
T
P
K
V
D
K
E
A
Q
V
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
93.3
N.A.
73.3
N.A.
60
53.3
N.A.
N.A.
60
N.A.
0
N.A.
13.3
6.6
13.3
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
N.A.
73.3
N.A.
40
N.A.
33.3
13.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
8
8
8
0
0
0
0
15
8
8
0
8
% A
% Cys:
8
15
0
0
0
0
0
8
0
8
0
0
0
0
0
% C
% Asp:
8
8
8
15
0
8
0
8
15
8
0
8
8
0
0
% D
% Glu:
0
8
0
8
50
22
43
0
8
8
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
29
8
0
0
8
0
0
% F
% Gly:
0
0
15
36
0
0
0
15
8
8
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
36
0
15
0
8
8
0
0
8
0
0
0
15
0
0
% I
% Lys:
0
8
0
8
8
22
8
15
0
0
8
43
0
50
15
% K
% Leu:
15
8
0
15
0
0
8
0
8
0
36
15
8
8
15
% L
% Met:
0
0
22
0
0
15
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
8
0
0
15
8
0
0
0
0
% N
% Pro:
0
15
0
0
0
0
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
8
0
0
0
0
8
8
0
0
0
0
43
22
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
8
0
8
0
8
0
% R
% Ser:
0
29
8
0
8
0
8
43
8
29
0
8
0
8
0
% S
% Thr:
0
0
0
0
8
15
0
0
0
15
8
0
8
8
8
% T
% Val:
15
0
22
8
8
0
0
0
8
0
22
0
0
0
58
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
15
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _